Ever wonder how bacteria can grow enough to produce an infection in the bladder? There aren’t a lot of intact components in urine. You have to have the four nucleic acids that compose DNA to be able to copy your DNA to make a nucleus for your child.
Now we know that a few species can make their own guanine, one of the required nucleobases, from different compounds that can be found in urine. Take that enzyme away and they can’t overgrow and cause a problem. This opens up another whole pathway of potential UTI treatments. Hooray!